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Home > Products >  High purity 99% Afatinib,afatinib dimaleate (EGFR1/HER2 inhibitor) in stock CAS NO.850140-72-6 manufacturer

High purity 99% Afatinib,afatinib dimaleate (EGFR1/HER2 inhibitor) in stock CAS NO.850140-72-6 manufacturer CAS NO.850140-72-6

  • msdsMSDS/COA Download

  • Min.Order: 1 Gram
  • Payment Terms: D/A,D/P,T/T,Western Union,MoneyGram,Other
  • Product Details

Keywords

  • Afatinib
  • BIBW 2992; BIBW-2992; Tovok;
  • 439081-18-2

Quick Details

  • ProName: High purity 99% Afatinib,afatinib dima...
  • CasNo: 850140-72-6
  • Molecular Formula: C24H25ClFN5O3
  • Appearance: powder
  • Application: pharmaceutical
  • DeliveryTime: in stock
  • PackAge: According client's requirements
  • Port: any chinese port
  • ProductionCapacity: 1 Metric Ton/Month
  • Purity: 99%
  • Storage: keep sealed and keep from direct light
  • Transportation: shipping by DHL,UPS,FEDEX,TNT,EMS,EUB…
  • LimitNum: 1 Gram

Superiority

Product Description

 

Afatinib

 

Afatinib Brief Description

CAS No.:850140-72-6

MF:C24H25ClFN5O3

MW:485.9384032

Competitive price with high quality

Conforms to BP/USP/EP/FCC

 

Afatinib COA

ITEM

STANDARD

RESULTS

Appearance

Off-white powder

Off-white powder

Identification

HPLC ,NMR

Complies

Residue on Ignition

≤0.10%

0.05%

Loss on Drying

≤0.50%

0.15%

Heavy Metal

≤20ppm

<20ppm

Purity(HPLC)

≥99.0%

99.99%

Conclusion

It complies with Enterprise Standard

  

Medical Use

 

AfatIt has received regulatory approval for use as a treatment for non-small cell lung cancer,although there is emerging evidence to support its use in other cancers such as breast cancer.

 

In October 2010 a Phase III trial in NSCLC patients called Lux-Lung 5 began with this drug.Fall 2010 interim results suggested the drug extended progression-free survival threefold compared to placebo, but did not extend overall survival.In May 2012, the Phase IIb/III trial Lux-Lung 1 came to the same conclusion.

 

In January 2015 a Phase III trial in people with NSCLC suggested the drug extended life expactancy in stage IV NSCLC Adenocarcinoma with EGFR Mutation type del 19-positive tumors, compared to cisplatin-based chemotherapy by a year (33 months vs. 21 months).

 

Phase II results for breast cancer that over-expresses the protein human epidermal growth factor receptor 2 (Her2-positive breast cancer) were described as promising by the authors, with 19 of 41 patients achieving benefit from afatinib.[9] Double-blind Phase III trials are under way to confirm or refute this finding. Her2-negative breast cancers showed limited or no response to the drug.

 

 

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.

 

Our advantages:

 

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 

2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, 

and we have stock in there for transferring.

 

3,We have clients throughout the world.

1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.

2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.

3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.

Details

Shaanxi Mingqi Chemical Co., Ltd is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and intermediates. It has trade with other Asian countries and Europe, the Americas and African countries. Important exporters of pharmaceutical chemical raw materials and the world's latest importers of pharmaceutical raw materials.

    Shaanxi Mingqi Chemical Co., Ltd has always been adhering to the company to market-oriented, customer-centric, with professional and enterprising team spirit and the company's strong financial strength, to provide customers with fast, high quality and efficient services, and always " To benefit customers "for the purpose.

      In the pharmaceutical raw materials and intermediates export business, the company by virtue of years of accumulated experience and high quality and reasonable talent structure, accurate grasp of the market, not only with a number of well-known domestic production enterprises to establish a long-term stable strategic cooperative relations in the global pharmaceutical chemical raw materials And chemical intermediates on the market also won the loyal customer base and a very strong strategic partner, set up a professional image of the outsourcing of pharmaceutical procurement. On the basis of continuing to develop the existing export trade business, the Company has formulated the idea of establishing independent research and development center and constructing the production base of pharmaceutical and chemical products according to the future development trend of the pharmaceutical and chemical industry, and strives to establish the combination of R & D, manufacturing and trade Of the business development model.

      While actively expanding their business and creating economic profits, enterprises do not forget their social responsibility, and actively participate in greening trees, poor students and other social activities, and become a tradition for many years, creating a good social benefits.

 

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