Factory Supply Artesunate in stock CAS NO.88495-63-0

Product name: Artesunate
Synonym: Artesunatum
CAS NO.: 88495-63-0 
M.F. &M. W. : C19H28O8; 384.43 
Plants source: composites Artemisia annua L. leaf. 
Appearance: white crystal powder
Melting point:132℃-135℃, odorless, bitter taste
Solubility: freely soluble in chloroform, soluble in acetone, slightly soluble in methanol or ethanol, practically insoluble in water.

Artesunate is a water-soluble, semi-synthetic derivative of the sesquiterpine lactone artemisinin with anti-malarial, anti-shistosomiasis, antiviral, and potential anti-neoplastic activities. Upon hydrolysis of artesunate's active endoperoxide bridge moiety by liberated heme in parasite-infected red blood cells, reactive oxygen species and carbon-centered radicals form, which have been shown to damage and kill parasitic organisms. Additionally, in vitro studies demonstrate that this agent induces DNA breakage in a dose-dependent manner. Artesunate has also been shown to stimulate cell differentiation, arrest the cell cycle in the G1 and G2/M phases, inhibit cell proliferation, and induce apoptosis through mitochondrial and caspase signaling pathways. Artemisinin is isolated from the plant Artemisia annua.

Function

1. With function of controlling of vivax malaria and falciparum malaria symptom, as
well as treatment of chloroquine-resistant strain of insect.
2. With function of oxidant. artemisinin is reduced by catalase,dithiothreitol and
alpha tocopherol.
3. With the function of antibacterial, artemisinin has anti-influenza virus effect.

4. With the function of anti-parasite, artemisinin on the role of anti-schistosomiasis
and leptospirosis.

Application

1.Artesunate is an antimalarial agent. It is a water-soluble hemisuccinate derivative of dihydroartemisinin.

2.Artemisinin is a sesquiterpene lactone isolated from Artemisia annua, a herb that has traditionally been used in China for the treatment of malaria.
3.Artesunate and its active metabolite dihydroartemisinin are potent blood schizonticides, active against the ring stage of the parasite.
4.Artesunate is ideal for the treatment of severe malaria, including cerebral malaria. It is also active against chloroquine and mefloquine resistant strains of P. falciparum.

Specification

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.

Our advantages:

1, High quality with competitive price:
1) Standard:BP/USP/EP/Enterprise standard
2) All Purity≥99%
3) We are manufacturer and can provide high quality products with factory price.

2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment.Tracking number available
2) Secure and discreet shipment.Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe,
and we have stock in there for transferring.

3,We have clients throughout the world.
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.

Shaanxi Mingqi Chemical Co., Ltd is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and intermediates. It has trade with other Asian countries and Europe, the Americas and African countries. Important exporters of pharmaceutical chemical raw materials and the world's latest importers of pharmaceutical raw materials.

Shaanxi Mingqi Chemical Co., Ltd has always been adhering to the company to market-oriented, customer-centric, with professional and enterprising team spirit and the company's strong financial strength, to provide customers with fast, high quality and efficient services, and always " To benefit customers "for the purpose.

In the pharmaceutical raw materials and intermediates export business, the company by virtue of years of accumulated experience and high quality and reasonable talent structure, accurate grasp of the market, not only with a number of well-known domestic production enterprises to establish a long-term stable strategic cooperative relations in the global pharmaceutical chemical raw materials And chemical intermediates on the market also won the loyal customer base and a very strong strategic partner, set up a professional image of the outsourcing of pharmaceutical procurement. On the basis of continuing to develop the existing export trade business, the Company has formulated the idea of establishing independent research and development center and constructing the production base of pharmaceutical and chemical products according to the future development trend of the pharmaceutical and chemical industry, and strives to establish the combination of R & D, manufacturing and trade Of the business development model.

While actively expanding their business and creating economic profits, enterprises do not forget their social responsibility, and actively participate in greening trees, poor students and other social activities, and become a tradition for many years, creating a good social benefits.