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High purity 99% Metronidazole powder in stock manufacturer CAS NO.443-48-1

  • Product Details

Keywords

  • Metronidazole 99%
  • Metronidazole
  • Metronidazole powder

Quick Details

  • ProName: High purity 99% Metronidazole powder i...
  • CasNo: 443-48-1
  • Molecular Formula: C6H9N3O3
  • Appearance: powder
  • Application: pharmaceutical
  • DeliveryTime: in stock
  • PackAge: According client's requirements
  • Port: any chinese port
  • ProductionCapacity: 1 Metric Ton/Month
  • Purity: 99%
  • Storage: keep sealed and keep from direct light
  • Transportation: shipping by DHL,UPS,FEDEX,TNT,EMS,EUB…
  • LimitNum: 1 Kilogram

Superiority

Introduction

1.Name:Metronidazole

2.Cas No.:443-48-1

3.Molecular Formula: C6H9N3O3

4.Molecular weight: 171.15

5.Melting Point (°C): 159-163°C

6.Water solubility: <0.1 g/100 mL at 20°C

7.Appearance: white powder

 

Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibacterial against anaerobic organisms,amoebicide and antiprotozoal. It is the drug of choice for first episodes of mild-to-moderate Clostridium difficile infection
Function

1. Metronidazole Powder has the function of  broad spectrum of anaerobic bacteria and peptides

2. Metronizalole Powder is mainly used for the prevention and treatment of infections caused by anaerobic bacteria, like  respiratory tract; digestive tract; the infection of enterocoelia and pelvic cavity; skin and soft tissue; bone and joint infection; endocarditis, brain abscess, blood poisoning and meningitis caused by bacteroides fragilis

3. Metronizalole Powder is widely used in the prevention and treatment of oral anaerobic bacteria infection

Application
Metronidazole has strong antibacterial effect to most anaerobic bacteria, used in the treatment of amebiasis,
trichomoniasis and anaerobic infections. 
Specification

Item

Specification

Result

Appearance

A white or yellowish crystalline powder

Comply

SOLUBILITY

SLIGHTLY SOLUBLE IN WATER,IN ACETONE,IN ALCOHOL AND IN METHYLENE CHLOROFORM,VERY SLIGHTLY SOLUBLE IN ETHER

COMPLY

IDENTIFICATION A),B)

C)  INFRARED

a)       MELTING POINT 159-163°C

b)      SPECIFIC ABSORBANCE 365-389

 

A) 160.1-160.5°C

B) 377

LOSS ON DRYING

0.5% MAX

0.15%

SULPHATE ASHES

0.1% MAX

0.07%

HEAVY METAL

20PPM MAX

LESS THAN 20PPM

RESIDUAL SOLVENTS

ETHANEDIOL LESS THAN 620PPM

LESS THAN 620PPM

PARTICLE SIZE

40-60MESH

COMPLY

APPEARANCE OF SOLUTION

SUSPENSION 2

AND SOLUTION GY6

COMPLY

RELATED SUBSTANCE

 

1) IMPURITY

0.1%MAX

0.06%

2)TOTAL IMPURITY

0.2%MAX

0.14%

3)DISREGARD LIMITED

0.01% MAX

PASS

ASSAY

99.0%-101.0% 

99.62%

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.

 

Our advantages:

 

1, High quality with competitive price:

1) Standard:BP/USP/EP/Enterprise standard

2) All Purity≥99%

3) We are manufacturer and can provide high quality products with factory price.

 

2, Fast and safe delivery

1) Parcel can be sent out in 24 hours after payment.Tracking number available

2) Secure and discreet shipment.Various transportation methods for your choice.

3) Customs pass rate ≥99%

4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, 

and we have stock in there for transferring.

 

3,We have clients throughout the world.

1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.

2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.

3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.

 

Specifications:

Name of product:  

Metronidazole         

Expiry Date:

 4 years

ITEMS

STANDARDS

RESULTS

Characteristics

a white or yellowish crystalline powder, slighting sobube in water, in acetone, in alcohol and in methylene, chloride, very slightly solube in ether

COMPLY

Identification

a) Melting point 159-163℃

161.1-161.3℃

b) Specific absorbance 365-395

b) 375

c) IR

c) COMPLY

d) The solution gives the reaction of primary aromatic amines

d) COMPLY

Appearance of solution

SUSPENSION Ⅱ

COMPLY

AND SOLUTION GY6

Related substances

Impurity:0.1MAX

0.02%

Total impurity:0.2MAX

0.06%

Heavy Metal

20PPM MAX

<20PPM

Loss on drying

0.5% MAX

0.19%

Particle size

40-80mesh

COMPLY

Assay

99.0%-101.0%

99.4%

Description of Metronidazole

Pharmacology
In addition to anti-trichomonas and anti-amoeba, in recent years, widely used in anti-anaerobic infections. This product nitro, anaerobic environment in the reduction of amino and anti-anaerobic bacteria show the role of aerobic bacteria or facultative aerobic bacteria is invalid. The following anaerobic bacteria have good antibacterial effect: ① Bacteroides, including Bacteroides fragilis; ② Fusobacterium; ③ Clostridium, including tetanus; ④ partial eubacteria; ⑤ digestive bacteria and digestion Streptococcus and so on. Oral absorption of good (> 80%), oral 250mg or 500mg, 1 ~ 2 hours serum drug concentration peak, respectively 6μg / ml and 12μg / ml. Intravenous infusion of the goods 15mg / kg, after every 6 hours infusion of 7.5mg / kg, plasma drug concentration reached a peak concentration of 25μg / ml, trough concentration of up to 18μg / ml. This product is widely distributed in the body, can enter the saliva, milk, liver abscess pus, can also enter the cerebrospinal fluid (normal CSF concentration of up to 50% of blood). In the body, the side chain oxidation or metabolism with glucuronic acid binding, 20% of the drug is not metabolized. Its metabolites also have a certain activity. Metronidazole and its metabolites by a large number of urinary excretion (60% of the total ~ 80%), a small amount of excretion from the feces (6% ~ 15%). T1 / 2 is about 8 hours.

Indications
Mainly for the treatment or prevention of anaerobic bacteria caused by the system or local infection, such as the abdominal cavity, digestive tract, female genital tract, lower respiratory tract, skin and soft tissue, bone and joint parts of anaerobic infections, sepsis, Membranitis, meningeal infection and the use of antibiotics caused by colitis is also effective. Treatment of tetanus and tetanus antitoxin (TAT) in combination. Can also be used for oral anaerobic infections.

 

 

 

Details

Our company is committed to the development of import and export trade in the production, operation and plant extracts of pharmaceutical raw materials and intermediates. It has trade with other Asian countries and Europe, the Americas and African countries. Important exporters of pharmaceutical chemical raw materials and the world's latest importers of pharmaceutical raw materials.

      Our company has always been adhering to the company to market-oriented, customer-centric, with professional and enterprising team spirit and the company's strong financial strength, to provide customers with fast, high quality and efficient services, and always " To benefit customers "for the purpose.

      In the pharmaceutical raw materials and intermediates export business, the company by virtue of years of accumulated experience and high quality and reasonable talent structure, accurate grasp of the market, not only with a number of well-known domestic production enterprises to establish a long-term stable strategic cooperative relations in the global pharmaceutical chemical raw materials And chemical intermediates on the market also won the loyal customer base and a very strong strategic partner, set up a professional image of the outsourcing of pharmaceutical procurement. On the basis of continuing to develop the existing export trade business, the Company has formulated the idea of establishing independent research and development center and constructing the production base of pharmaceutical and chemical products according to the future development trend of the pharmaceutical and chemical industry, and strives to establish the combination of R & D, manufacturing and trade Of the business development model.

      While actively expanding their business and creating economic profits, enterprises do not forget their social responsibility, and actively participate in greening trees, poor students and other social activities, and become a tradition for many years, creating a good social benefits.

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